Zegna Runner Blk Ermenegildo Techmerino White FdZOXqC
Ermenegildo Zegna’s heritage heavy brand sidles up to the newest technological innovation in this leather and merino fused running shoe. The Italian label offers these ultra light trainers, melded with a jacquard woven sock and nappa leather in a cut out pattern. Signature details remain: an applique rubber brand logo sits on the tongue, heel loop and rubber grip sole. Run with these beauties if you dare, or keep them mud free for citywear with a techie edge. Ermenegildo Zegna Techmerino running shoesRubber logo on tongue, heel and rubber gripSock like designLeather upper and lining Rubber soleComes with an Ermenegildo Zegna box with dust bagMade in Italy
Ermenegildo Techmerino Runner Zegna Blk White Ermenegildo Runner Techmerino Blk Zegna White Techmerino Blk Ermenegildo Zegna White Runner
2002 Sep 27;297(5590):2275-9.


Celiac Sprue, a widely prevalent autoimmune disease of the small intestine, is induced in genetically susceptible individuals by exposure to dietary gluten. A 33-mer peptide was identified that has several characteristics suggesting it is the primary initiator of the inflammatory response to gluten in Celiac Sprue patients. In vitro and in vivo studies in rats and humans demonstrated that it is stable toward breakdown by all gastric, pancreatic, and intestinal brush-border membrane proteases. The peptide reacted with tissue transglutaminase, the major autoantigen in Celiac Sprue, with substantially greater selectivity than known natural substrates of this extracellular enzyme. It was a potent inducer of gut-derived human T cell lines from 14 of 14 Celiac Sprue patients. Homologs of this peptide were found in all food grains that are toxic to Celiac Sprue patients but are absent from all nontoxic food grains. The peptide could be detoxified in in vitro and in vivo assays by exposure to a bacterial prolyl endopeptidase, suggesting a strategy for oral peptidase supplement therapy for Celiac Sprue.

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