Backpack Embroidery Stella Tropical McCartney Black Falabella OAxwAgaqY8
As always, Stella McCartney fashions contemporary offerings for the modern woman without eschewing the ethical ambitions that the brand was built on. This black Falabella tropical embroidery backpack features a round top handle, a double top zip closure, a front zip compartment, adjustable shoulder straps, a main internal compartment, an internal zipped pocket, curb chain and leather woven details, tropical embroidery patches and a front embossed leather patch.
Embroidery Falabella Black McCartney Tropical Backpack Stella Embroidery Falabella Black Tropical Stella Backpack McCartney Black Backpack Embroidery Stella McCartney Falabella Tropical
2002 Sep 27;297(5590):2275-9.

Abstract

Celiac Sprue, a widely prevalent autoimmune disease of the small intestine, is induced in genetically susceptible individuals by exposure to dietary gluten. A 33-mer peptide was identified that has several characteristics suggesting it is the primary initiator of the inflammatory response to gluten in Celiac Sprue patients. In vitro and in vivo studies in rats and humans demonstrated that it is stable toward breakdown by all gastric, pancreatic, and intestinal brush-border membrane proteases. The peptide reacted with tissue transglutaminase, the major autoantigen in Celiac Sprue, with substantially greater selectivity than known natural substrates of this extracellular enzyme. It was a potent inducer of gut-derived human T cell lines from 14 of 14 Celiac Sprue patients. Homologs of this peptide were found in all food grains that are toxic to Celiac Sprue patients but are absent from all nontoxic food grains. The peptide could be detoxified in in vitro and in vivo assays by exposure to a bacterial prolyl endopeptidase, suggesting a strategy for oral peptidase supplement therapy for Celiac Sprue.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Support Center